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Onee-Chan – Mihari’s Experiment Turns Mahiro Oyama Into a Girl

Daniel Sams by Daniel Sams
August 4, 2023
in Entertainment
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Mihari's Experiment
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One morning, a teenage hikikomori boy found himself transformed into a female by his mad-scientist sister. Now, she has him enrolled in a Yuri class to see if there’s any way he can reverse the change back.

Miharis experiment on Oneechan

Mihari introduces him to Kaede Hozuki, an elderly lady from their village who helps care for him by cooking and bathing him, then watching a film together.

Table of Contents

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  • Onee-chan’s Messages
  • Mahiro’s Experiment
  • Mihari’s Experiment
  • Miyo’s Experiment

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Onee-chan’s Messages

Japanese culture values respect for elders; therefore the terms onee-chan and onii-chan are frequently used by younger siblings to show love and appreciation. Such respect forms an integral part of the family hierarchy. Therefore younger siblings often refer to older family members with these terms when speaking directly to them. Read about Onee-chan Wa Game O Suruto Hito Ga Kawaru Onee-chan.

Mahiro Oyama is an otaku and NEET living with his scientist younger sister Mihari. One day, Mihari gives Mahiro something which causes him to wake up as a woman; now he must learn how to live as one while also trying to maintain his life as usual.

Cartoon and manga depictions of sibling relationships can often be unfavorable or sexualized, having negative repercussions for those involved. Therefore, understanding their depiction and being mindful when viewing media content are crucial in order to consume media critically and avoid unknowingly reinforcing negative stereotypes about siblings. Their intent and context ultimately dictate their impact.

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Mahiro’s Experiment

Mahiro Oyama was just your average erotic-game fan until his eccentric little sister Mihari decided to conduct one of her experiments on him and see what would happen! What followed is something even Mahiro himself found somewhat surprising – he awoke as a woman!

While initially resisting Mihari’s new rules for him? such as taking more frequent showers and going outside more frequently? he soon adapts to life as a teenager girl, wearing girly clothing like sundresses and pleated skirts with knee-high socks. Furthermore, he becomes aware of his body gradually changing into one that is taller and bustier.

Momiji, Kaede’s tomboyish middle school sister, becomes close with Mahiro after they meet during middle school. Although attracted by Mahiro’s advances toward her, Momiji manages to remain polite as they spend time shopping and going to the movies together before helping tidy his room when asked over by Mahiro.

Mihari’s Experiment

Mihari is a child prodigy who skipped several grades. As a part of an experiment, she developed a drug to change her older brother into a woman – something Mihari loves doing with her little sister as an experiment. With Mihari’s help, her sibling will regain their social butterfly qualities after living an isolated lifestyle for so long.

Mihari is going through her own challenges as well, such as dealing with having a daughter that looks exactly like her and trying to be as loving and motherly as possible in raising her.

This series is ideal for fans of gender-bender manga. The anime features comedic scenes involving bathing scenes, visits to the bathroom and daily struggles of being an isolated individual, as well as having some strong lessons about self-care for its protagonist. Shingo Fujii (Mushoku Tensei Jobless Reincarnation Episode 11 storyboards) does an outstanding job pacing his episodes.

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Miyo’s Experiment

Mihari is a grade-skipping wunderkind scientist who has been conducting experiments on animals with the purpose of testing out sex change drugs, which she accidently administered to Mahiro and transformed him into female form. Mahiro wasn’t too pleased about it at first; but Mihari claims she is trying to help socialize him more thoroughly as part of her research project.

He and his friends Momiji, Asahi and Miyo spend the night at Mihari?s younger sister?s home. While conversing about school life and playing video games, Mahiro becomes unwittingly involved in an intense game of rock-paper-scissors that causes Mahiro to urinate in the middle of the night.

Mahiro discovers that he can no longer do the things he once enjoyed doing, such as visiting the boys? restroom or changing in front of other girls. In turn, this gives him newfound appreciation for his own decup assets.

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Daniel Sams

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